Liver & Hepa-Guard

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Liver & Hepa-Guard is a proprietary blend of herbs and nutrients designed to support healthy liver function. Dr. Verghese's Liver Formula contains Milk Thistle Extract, which has been shown in clinical and non-clinical studies to support the liver, as measured by standard liver enzyme laboratory tests. In addition, Dr. Verghese's Liver Formula contains N-Acetyl Cysteine and Methionine, two amino acids known to enhance the production of glutathione in the liver. Glutathione, a major cellular antioxidant plays an essential role in liver detoxification mechanisms. Also included in this Liver Formula are other herbs (Schisandra, Bupleurum, and Scute). *

  • Liver Support*
  • Clinically Developed
  • Comprehensive Formula
  • A Dietary Supplement


  • LIKELY USERS:
    People with exposure to toxins that stimulate liver activity; People with exposure to infections that may have damaged liver tissue
    KEY INGREDIENT (S): Milk Thistle extract (Silymarin), Glutathione, NAC, Bupleurum extract, Grape Seed Extract, Dandelion Root extract, Artichoke Leaf, Schisandra and about a dozen additional herbs, along with synergistic ingredients
    MAIN PRODUCT FEATURES: This formula was developed by a physician based on his clinical experience.
    Artichoke leaf has antioxidant properties and restores healthy growth to liver cells.
    Bupleurum may promote normal cell growth, immune function and is a staple of Chinese liver formulas.
    Dandelion Root may serve as a natural down-regulator of inflammatory chemicals in the body.
    NAC supports liver Glutathionestores (antioxidant, detoxifier, heavy metal chelator).
    Schisandra protects liver cells from toxins and may help to regenerate damaged cells.

    Milk thistle?s antioxidant Silymarin improves liver function tests and protects liver cells against oxidative damage. It also protects liver cells by blocking and removing toxins from the liver. Silymarin aids in regenerating injured liver cells and blocks fibrosis.

    OTHER IMPORTANT ISSUES: Samuel Verghese, M.D. (AM), Ph.D., BCIA-EEG, DAAPM, holds a degree in Alternative Medicine and specializes in Nutritional, Ayurvedic and other Alternative Health Solutions. He is certified as a BCIA-EEG Associate Fellow.

    AMOUNT TO USE: Three or more capsules a day, preferably with meals.

    COMPLEMENTARY PRODUCTS: Antioxidants (supports liver detoxification), Alpha Lipoic Acid, EGCg Green Tea Extract, Astragalus, medicinal mushrooms (shiitake, reishi), SAM-e (may improve bile flow and promotes methylation to detoxify chemicals), TMG, lecithin, thymus glandular extract, Cordyceps.

    AVOID: acetaminophen, alcohol, iron supplements (also red meat, fortified flour)

    CAUTIONS: This formula should not be used by pregnant women, nursing mothers children or those with liver problems unless recommended under the supervision of a healthcare professional. Please notify your physician about your supplement use if you are using any drugs!
    Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

    REFERENCES:

    1. Salmi HA, Sarna S. Effect of silymarin on chemical, functional and morphological alterations of the liver. A double-blind controlled study. Scand J Gastroenterol 1982;17:517?1.
    2. Feher J, Deak G, Muzes G, et al. Liver-protective action of silymarin therapy in chronic alcoholic liver diseases. Orv Hetil 1989;130:2723? [in Hungarian].
    3. Muzes G, Deak G, Lang I, et al. Effect of silymarin (Legalon) therapy on the antioxidant defense mechanism and lipid peroxidation in alcoholic liver disease (double blind protocol.) Orv Hetil 1990:131:863? [in Hungarian].
    4. Velussi M, Cernigoi AM, De Monte A, et al. Long-term (12 months) treatment with an anti-oxidant drug (silymarin) is effective on hyperinsulinemia, exogenous insulin need and malondialdehyde levels in cirrhotic diabetic patients. J Hepatol 1997;26:871?.
    5. Lieber CS. Nutrition in liver disorders. In: Shils ME, Olson JA, Shike M, Ross AC (eds). Modern Nutrition in Health and Disease, 9th ed. Baltimore, MD: Williams and Wilkins, 1999, 1179?0.
    6. Rodriguez-Moreno F, Gonzalez-Reimers E, Santolaria-Fernandez F, et al. Zinc, copper, manganese, and iron in chronic alcoholic liver disease. Alcohol 1997;14:39?4.
    7. Gibbs K, Walshe JM. Studies with radioactive copper (64 Cu and 67 Cu); the incorporation of radioactive copper into caeruloplasmin in Wilson?s disease and in primary biliary cirrhosis. Clin Sci 1971;41:189?02.
    8. Lieber CS. Nutrition in liver disorders. In: Shils ME, Olson JA, Shike M, Ross AC (eds). Modern Nutrition in Health and Disease, 9th ed. Baltimore, MD: Williams and Wilkins, 1999:1179?0.
    9. Halsted CH. Alcohol: medical and nutritional effects. In Ziegler EE, Filer LJ (eds). Present Knowledge in Nutrition, 7th ed. ILSI Press, Washington, DC, 1996, 553.
    10. Blum AL, Doelle W, Kortum K, et al. Treatment of acute viral hepatitis with (+)-cyanidanol-3. Lancet 1977;2:1153?.
    11. Suzuki H, Yamamoto S, Hirayama C, et al. Cianidanol therapy for HBs-antigen-positive chronic hepatitis: a multicentre, double-blind study. Liver 1986;6:35?4.
    12. Tang W, Eisenbrand G. Chinese Drugs of Plant Origin. Berlin: Springer Verlag, 1992. (Astragalus)
    13. Hobbs, C. Medicinal Mushrooms. Santa Cruz, CA: Botanica Press, 1995, 96?07.
    14. Harada T, Kanetaka T, Suzuki H, Suzuki K. Therapeutic effect of LEM (extract of cultured Lentinus edodes mycelia) against HBeAg-positive chronic hepatitis B. Gastroenterol Int 1988;1(suppl 1):abstract 719. 15. Kelly GS. Clinical applications of N-acetylcysteine. Altern Med Rev. Apr1998;3(2):114-27.
    16. Montanini S, et al. Use of acetylcysteine as the life-saving antidote in Amanita phalloides (death cap) poisoning. Case report on 11 patients. Arzneimittelforschung. Dec1999;49(12):1044-7.
    17. Buckley NA, et al. Oral or intravenous N-acetylcysteine: which is the treatment of choice for acetaminophen (paracetamol) poisoning? J Toxicol Clin Toxicol. 1999;37(6):759-67. 18. Girardi G, Elias MM. Effectiveness of N-acetylcysteine in protecting against mercuric chloride-induced nephrotoxicity. Toxicology. Apr1991;67(2):155-64.
    19. Berkson MB. Alpha-Lipoic Acid (Thioctic Acid): My Experience With This Outstanding Therapeutic Agent. Journal of Orthomolecular Medicine. 1998;13(1):44-48.
    20. Breithaupt-Grogler K, et al. Dose-proportionality of oral thioctic acid--coincidence of assessments via pooled plasma and individual data. Eur J Pharm Sci. Apr1999;8(1):57-65.
    21. Gebhardt R. Antioxidative and Protective Properties of Extracts from Leaves of the Artichoke (Cynara scolymus L.) Against Hydroperoxide-induced Oxidative Stress in Cultured Rat Hepatocytes. Toxicol Appl Pharmacol. Jun1997;144(2):279-86.
    22. Adzet T, et al. Hepatoprotective Activity of Polyphenolic Compounds From Cynara scolymus Against CCl4 Toxicity in Isolated Rat Hepatocytes. J Nat Prod. Jul1987;50(4):612-17.
    23. Gebhardt R. Antioxidative and protective properties of extracts from leaves of the artichoke (Cynara scolymus L.) against hydroperoxide-induced oxidative stress in cultured rat hepatocytes. Toxicol Appl Pharmacol. Jun1997;144(2):279-86.
    24. Khadzhai I, et al. Effect of Artichoke Extracts on the Liver. Farmakol Toksikol. Nov1971;34(6):685-87.
    25. Newall CA, et al. Herbal Medicine: A Guide for Health-Care Professionals. Cambridge: Pharmaceutical Press; 1996:36-37.
    27. Newall CA, et al. Herbal Medicines: A Guide for Health Care Professionals. London: The Pharmaceutical Press;1996:96-97.
    28. Bradley PR, ed. British Herbal Compendium. Vol.1. Bournemouth: British Herbal Medicine Association;1992:73-74.
    29. Newall CA, et al. Herbal Medicines: A Guide for Health Care Professionals. London: The Pharmaceutical Press;1996:96-97.

    Nutrition Info
    Serving Size: 3 Capsules

    Servings Per Container: 30

    Amount Per Serving

    % Daily Value*

    Calories

    10

    Total Carbohydrate

    1 g

    <1%*

    Dietary Fiber

    0.7 g

    3%*

    Vitamin C (from Ascorbyl Palmitate)

    12 mg

    20%

    Milk Thistle (Standardized Extract) (Seeds)
    (Silybum marianum) (min. 80% Silymarin)

    300 mg

    Proprietary Herbal-Nutrient Blend:
    Artichoke (Cynara scolymus) (Leaf), Beet (Beta vulgaris) (Leaf),
    Black Radish (Raphanus sativus) (Root), Bladderwrack (Fucus versiculosus)
    (Whole Plant), Raspberry (Rubus idaeus) (Leaf), Phosphatidyl Choline (soy),
    Pancreatic Enzymes), Blue Flag (Iris versicolor) (Root), Cleavers (Galium aparine)
    (Aerial Parts)

    250 mg

    L-Glutathione (Free-Form) (Reduced)

    100 mg

    N-Acetyl Cysteine (NAC)

    100 mg

    Bupleurum (4:1 Concentrate) (Root) (Bupleurum chinense)

    100 mg

    Grape Seed (Standardized Extract) (Vitis vinefera) (min. 80% Polyphenols)

    100 mg

    Dandelion (4:1 Concentrate) (Root) (Taraxacum officinale)

    100 mg

    L-Carnitine Base

    50 mg

    Scute (4:1 Concentrate) (Root) (Sculellariae baicalensis)

    50 mg

    Pueraria (4:1 Concentrate) (Flower) (Pueraria thunbergiana)

    50 mg

    Schisandra (Fruit) (Schisandra chinensis)

    50 mg

    Barberry (Root Bark) (Berberis vulgaris)

    30 mg

    Turmeric (Root) (Curcuma longa)

    30 mg

    L-Methionine

    20 mg

    * Percent Daily Values are based on 2,000 calorie diet.
    † Daily Value not established.

    Other Ingredients: Cellulose, Gelatin (capsule), Stearic Acid (vegetable source), Magnesium Stearate (vegetable source) and Silica.
    Suggested Usage: As a dietary supplement, take 3 capsules daily, preferably with food.
    Contains no: sugar, salt, starch, yeast, wheat, gluten, milk, egg, shellfish or preservatives.

    Do Not Eat Freshness Packet. Keep in Bottle.

    Disclaimers: *These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or p

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